ExCPT Pharmacy Technician Practice Exam 2026 – Complete Prep Resource

For Schedule II controlled substances, federal regulations explicitly state that no refills are permitted. When a prescriber writes a prescription for a Schedule II drug, the patient needs to obtain a new prescription each time they need to refill the medication. This rule is in place due to the high potential for abuse and dependence associated with these substances, which include drugs like oxycodone and morphine.

Because of the strict regulations surrounding Schedule II medications, it is essential for patients to follow the prescribed regimen closely and consult their healthcare provider for any changes or needs for further prescriptions. The prohibition of refills serves as a safeguard to help monitor usage and minimize the risk of misuse.